[HTML][HTML] Effects of CYP2C19 Genotype on Outcomes of Clopidogrel Treatment
… benefit from clopidogrel treatment as compared with placebo than did noncarriers (rate of
primary outcome among carriers… The effect of clopidogrel on bleeding did not vary according to …
primary outcome among carriers… The effect of clopidogrel on bleeding did not vary according to …
Reduced-function CYP2C19 genotype and risk of adverse clinical outcomes among patients treated with clopidogrel predominantly for PCI: a meta-analysis
JL Mega, T Simon, JP Collet, JL Anderson, EM Antman… - Jama, 2010 - jamanetwork.com
… In totality, we were able to examine the association of CYP2C19 genotype and clinical
outcomes in 9685 patients who initiated guideline-recommended treatment with clopidogrel, …
outcomes in 9685 patients who initiated guideline-recommended treatment with clopidogrel, …
Clinical Pharmacogenetics Implementation Consortium Guideline for CYP2C19 Genotype and Clopidogrel Therapy: 2022 Update
… -analyses on CYP2C19 genotype-guided antiplatelet therapy with clinical outcomes data …
interpretation of clinical CYP2C19 genotype test results to guide clopidogrel prescribing. As …
interpretation of clinical CYP2C19 genotype test results to guide clopidogrel prescribing. As …
Clinical Pharmacogenetics Implementation Consortium Guidelines for CYP2C19 Genotype and Clopidogrel Therapy: 2013 Update
… linking CYP2C19 genotype with clinical outcomes among … know their CYP2C19 genotype
status at the time of treatment, and … management for those in whom genotype is available or for …
status at the time of treatment, and … management for those in whom genotype is available or for …
CYP2C19 genotype, clopidogrel metabolism, platelet function, and cardiovascular events: a systematic review and meta-analysis
… effect-modification placebo-controlled trials included in this meta-analysis, there was no
evidence of a clopidogrel treatment × CYP2C19 genotype … risk of cardiovascular outcomes in the …
evidence of a clopidogrel treatment × CYP2C19 genotype … risk of cardiovascular outcomes in the …
[HTML][HTML] Clopidogrel therapy and CYP2C19 genotype
L Dean, M Kane - 2018 - europepmc.org
… loss-of-function allele carriers and poorer outcomes when treated with clopidogrel as … PCI,
where CYP2C19 genotype was assessed and included in the outcomes, and clopidogrel was …
where CYP2C19 genotype was assessed and included in the outcomes, and clopidogrel was …
Clinical Pharmacogenetics Implementation Consortium Guidelines for Cytochrome P450–2C19 (CYP2C19) Genotype and Clopidogrel Therapy
SA Scott, K Sangkuhl, EE Gardner… - Clinical …, 2011 - Wiley Online Library
… The purpose of these guidelines is to provide information regarding the clinical use of
CYP2C19 genotype test results in patients requiring antiplatelet therapy. Detailed guidelines for …
CYP2C19 genotype test results in patients requiring antiplatelet therapy. Detailed guidelines for …
… genotype has a greater effect on adverse cardiovascular outcomes following percutaneous coronary intervention and in Asian populations treated with clopidogrel: a …
… Clopidogrel indication and ethnic population have been proposed to influence the effect
of CYP2C19 genotype. Methods and Results— …
of CYP2C19 genotype. Methods and Results— …
… Between CYP2C19 Genotype and Pharmacodynamics in Patients Treated With Ticagrelor Versus Clopidogrel: The ONSET/OFFSET and RESPOND Genotype …
… of clopidogrel, there was no effect of CYP2C19 genotype during ticagrelor therapy. …
Our results are consistent with the findings of the genetic substudy of the PLATO trial, where …
Our results are consistent with the findings of the genetic substudy of the PLATO trial, where …
Effect of CYP2C19 Genotype on Ischemic Outcomes During Oral P2Y12 Inhibitor Therapy: A Meta-Analysis
NL Pereira, C Rihal, R Lennon, G Marcus… - Cardiovascular …, 2021 - jacc.org
… The aim of this study was to examine the effect of CYP2C19 genotype on clinical outcomes
in … intervention (PCI), comparing those treated with ticagrelor or prasugrel versus clopidogrel. …
in … intervention (PCI), comparing those treated with ticagrelor or prasugrel versus clopidogrel. …